Africa1, would love to see some pictures and read about your Beretta 458 double some time. I am extremely fond of the Beretta doubles but haven't heard from anyone that owns one.

My choice- for hunting
.22lr
.375 H&H
12gauge (what else are you going to use on ducks etc.)
Outside Australia I would include a .416 Rigby, preferrably in double rifle.

For fun I'd add a lever gun in 357mag. and long range plinking, because ammo is cheep, an accurate .223
Just realised that is six, so I'll lose the .223