Enjoyed reading the responses thus far and having given it some thought many times in my life time. I have the following observations, if at all possible stick with the same action in everyting, except perhaps the 22lr and the shot gun. in my case and if I had to, I could live with 4 guns, 2 Mauser bolt action rifles in 6mm Rem, 300 WM., a 16 gau. on a Mauser 98 and a 22 lr either bolt or semi-auto. The versatility of the loads available for the 6mm & .300 and the overlapping game sizes vs availale loads pretty well covers anything one might hunt anywhere. Having said all that I will keep all my babies as long as I can. A list follows 22LR, 22-250, 220 Swift, 6mm REM, 7x57, 32.20, 303 British, 300 WM, 38.55 and "several" shotguns. --- John303