Yours sounds like a very fine bolt rifle and in my favorite caliber too.

For starters, you might try Federal's 300 H&H factory load. It shoots great in my gun and uses a 180gn Nosler Partition @ 2880fps from a 24" barrel. (Since my Ruger #1's got a 26" barrel, this load's over 2900fps). Truthfully, 2880fps is more downloaded than it needs to be.

In handloads, I'm still working with the 200gn Nosler's near book max, using 66grs of IMR 4831 (as always start lower in your gun). I'm also testing Hornady's 220gn bullets w/ R-22.

I think the 300 H&H is a grand old caliber, one that's still equally as effective on game as any of the newer 300 "super" magnums, without the added shoulder-bruising recoil and excess muzzle blast.

Enjoy yours.