You can use 200gr. Nosler's for everything in a .300 MAg. My buddy uses little else, unless he's hunting with his .375 or .45/70. According to him, the 200gr. Partitions start to open on deer and drop them in their tracks but don't blow them up like lighter bullets tend to do. They're perfect medicine for Elk and Moose, but the larger bores still work better on the big Bears.