I have heard the 60gr. PARTITION requires a faster than the old norm of 16" & 14" twists, as in a 12".
That bullet, or the TSX in 45gr. or 50gr. would likely be even better.
I've a friend who has shot 3 whitetail bucks with his .22-250 using the 45gr. TSX. These were in the middle of fields and 2 dropped on the spot. The third took 4 steps. All exits with 3/4" hole.