The 250 gr. Barnes bullets were made a long time ago and, I believe, were specifically for the velocities you can get in an '06 case. Most likely your poor performance out of the Weatherby case is do to the excess speed therefrom. This was a very typical problem with Weatherby cartridges back when they were first being designed and the 250 gr Barnes dates from that period. Nothing wrong with the bullet in its proper case but in the Weatherby you get blowup. That's why if you shoot Wby, you need premium bullets.