Armbar
I have a ruger MKII Target in 22250.
Straight out of the box with reloads I get 3/4 groups.
Am also fairly certain that with a better scope and conditions it probably shoots less. But the rifle is often not the limiting factor.
Good Luck

22250 is very good for head and neck shots on small to medium game. I wouldn't rely on chest shots on anything larger than a dingo.