Do not own (or need or want) a Blaser, but do own and use Miroku/Winchester 1886 in 45-70(458 2.1) and 1886 in 45-90(458 2.4) AND 1895 in .405 WCF with chamber extended to properly handle Woodie 400 grain bullets.
All have been to Africa and taken Cape buff and the 45-90 an ele. With the Woodie 400 grain solids, so can the .405.
Our bullet testing expedition showed that most heavy 400+ grain .458 bullets would kill buff, but that the cast bullets were more likely to shed weight, break apart, and deviate from course.

On ele, the most reliable were North Fork and Punch bullets; frontal brain shots from these shot through the brain skull, and on into the body and retrieval was accomplished by cutting them from the ele body.
My favorite solid for the .45-70 is the 450 grain Punch bullet at 2000 + fps; these PUNCH through a 5/8 in steel plate and ele heads.
Fave non solid tough bullet is the Alaska bullet works 450 grain JSP or FMJ at 2150 fps for all but the ele frontal brain shot where they only stun and do not penetrate the brain.

Blaser rifles ? I have nothing against a Blaser, but with a Winchester 1886, who needs them?