Agree--while it makes for interesting discussion, there is no such thing IMHO. Largely dependent on what you are hunting, where you are hunting, etc... Yes, there are a few that will work for everything but are they "perfect"???... I can't think of one that is perfect for all types of game, terrain, etc... The 375H&H is a really fine cartridge. Works well on larger game and if necessary will kill up to elephant..are there others that will work better, hit harder, etc??? Absolutely ...

While dead is dead, there is that crazy word again, "perfect"... and it is NOT perfect at least in my experience...can certainly kill all of them, but perfection is not there for any cartridge, again, IMHO...

Ripp