I would cast my vote for a .375H&H. It will shoot as far as you'd ever want to shoot and it will scale up nicely to take the larger antelope. Kudu, gemsbok, zebra, and if course eland are pretty darn big and a bit of extra weight and diameter is a good thing in a premium bullet. I used my .375 H&H Kodiak to take a warthog and Impala using 300 grain TSX with great effect and not a lot of wasted meat which at least to me shows it scales down nicely as well. With the short stainless barrel and laminate stock, it is ideal to push through the tag alders in driving rain in the far north country of north America hunting moose if that type of miserable wet condition hunting turns your crank. Likewise, no issues with hunting the ultra humid jungles of the world. Ammo is widely available world wide. Versatile is the word!!