I'm not sure that's what Rolf meant, but fascinating nonetheless.

Funny somebody should bring up a 458, I've been considering a 300blk, with cast 200-240 grain projectiles, but a 458 with 400-500 grain cast is something I'm very interested in.....

I can't think of it as anything other than a 22 with more punch, and certainly I agree brain shots are to be the SOP.

I bought a Remington to rebarrel, but made that most critical mistake - I shot the donor......