You aren't the only one who uses a 338WM well and it works.

Anything through the heart kills them but I reckon
the 375H&H makes a much bigger hole and shock when
it kits than a 338WM on Buffalo.

Agree, bigger is better.

Horses, Jesus they go down ! I've used 9.3 X 64 and 500/465- on a charging Stallion that didn't look like he was going to stop !!!