The 180 nosler partician will get a deserved vote because there's so much good experience with it. It's a great bullet for the .30-06.

My preference is for the Swift A-Frame 200 grain and I can drive it at 2,700'/sec with a minor amount of creative loading from a featherweight barrel of 22". A featherweight rifle that shoots well under minute of Duiker to 300 yards with 3,250 ft-lb of energy is a very fine rifle indeed. Some of these plains game animals are really big and the heavier bullet gives me the assurance I want.