I hear you gryphon - I'd think an accurate (good chance) .308 or '06 would be hard to beat for all-round hunting. 150gr. or 165gr. TSX - running 2,950fps to 3,050fps - long range, close range - with the scopes today, take proper aim and take your shot.

Of course, that said, borrow my Daughter's .260 with 120gr. TSX running 3,000fps - any game, any range likely to be taken by me. I'd have to leave the 9.3 or .375 at home, though.