Yes, it doesn't always work out like that.

I used to shoot Field Rifle with a .308 and it was zeroed at 200m and was spot on at 25m.
The target distances are 25, 50, 100, 200m, so I would aim directly at 25 & 200, hold at 6 oclock on the ten ring for 50m and at 6 oclock on the 9 ring at 100m.