Szihn, seeing as how you're the bullet maven, what's your opinion on using .257 magnum 100-gr. Hornady Interbond spitzers on animals up to and including Kudu?

If the sun is bright, the air is clean, and I hold my mouth right, I can hit the right spot, so accuracy isn't a problem. I'm just curious if you think very high velocity and proper bullets (Barnes X included) will do the job on large mammals. I'm going to use the .257 on a leopard in August, and am kicking around the idea of leaving my Ruger .416 at home.

Most of my hunting has been with large boomers, so this .257 is a totally new experience.