I shoot both the .338 winchester magnum and the .375 ruger. When it comes to things that bite, stomp, gore and such, I will be sticking with the .375 ruger. I have conducted some very informal tests and arrived at that conclusion. I know that ballistics seem comparable, but in my opinion the .375 caliber, whether ruger, or H&H, or one of the other obscure chamberings is a superior dangerous game caliber. The whelen is a caliber I have always been interested in. If I ever find a rifle I like in that caliber I might be tempted to give it a whirl.